Best Nonprofit CRM Systems in 2025 That Help You Raise More and Do More

By Katie Wilson

February 12, 2025

Comparing Industry Leading Nonprofit CRM Systems

Choosing the right nonprofit CRM system is like picking the perfect partner for your organization—it needs to align with your goals, streamline operations, and help you build lasting relationships with donors. With so many options out there, finding the right fit can feel overwhelming. Some CRMs cater to large-scale enterprise nonprofits, while others are built for small teams that need a simple, effective tool. Let’s break down some of the best nonprofit CRM systems and what makes each one stand out.

StratusLIVE 365 CRM: Best for Enterprise Nonprofits

If your nonprofit operates at a large scale, StratusLIVE 365 is built just for you. Designed on Microsoft Dynamics 365, it integrates directly with tools like Outlook, Teams, and SharePoint, making it easy to track donor relationships without bouncing between different platforms.

What really makes StratusLIVE shine is its AI-powered engagement scoring and donor insights. It helps nonprofits identify major gift prospects, track donor sentiment, and manage campaigns with real-time data analytics. And because it’s backed by Microsoft Azure, security and compliance are top-notch—something every nonprofit handling donor data should prioritize.

One of the best parts? It’s built for growth and complexity. Whether you’re managing large-scale fundraising efforts, corporate partnerships, or a federated nonprofit structure, StratusLIVE 365 scales with you. If your organization already lives in the Microsoft ecosystem, this CRM is a natural extension of the tools you use every day.

Salesforce Nonprofit Cloud: Highly Customizable, but Requires Work

Salesforce is a powerhouse in the CRM world, and its Nonprofit Cloud is a popular choice for organizations that want flexibility. If you love customizing dashboards, automating workflows, and integrating multiple third-party apps, Salesforce gives you the freedom to tailor it to your nonprofit’s needs.

But, and it’s a big but—Salesforce requires a lot of setup. Most nonprofits need a consultant to configure it properly, and while that customization is great, it can be overwhelming for organizations that don’t have a dedicated CRM administrator. The AI-powered donor insights and broad app marketplace are perks, but it’s important to consider whether your team has the time and resources to fully leverage Salesforce’s capabilities.

Blackbaud Raiser’s Edge NXT: Strong for Major Gift Fundraising

Blackbaud’s Raiser’s Edge NXT is well-known in the nonprofit space, and for good reason. It’s a powerful donor management tool with built-in fundraising and event planning features. If your organization focuses on major gifts, capital campaigns, and donor segmentation, Raiser’s Edge offers solid tools to track donor activity and build engagement.

That said, customization is a bit more limited compared to Salesforce or StratusLIVE. While it offers robust reporting and donor tracking, some nonprofits find it less flexible and sometimes hard to tailor reports for their needs. And while the platform itself is strong, customer support can be hit or miss, which is something to keep in mind if you need hands-on assistance.

Bloomerang: A Solid Choice for Small Nonprofits

For nonprofits that don’t need all the bells and whistles, Bloomerang is a great choice. It’s simple, easy to use, and built with donor retention in mind. One of its standout features is its built-in engagement scoring, which helps nonprofits identify which donors are at risk of dropping off so they can act before losing valuable supporters.

The downside? Bloomerang is more limited in terms of integrations and event management tools. It’s not as customizable as Salesforce or StratusLIVE, but for small to mid-sized nonprofits, it’s an easy-to-learn system that covers the basics well. If you’re looking for something lightweight and focused on donor relationships, this could be the right fit.

How These CRMs Compare Side by Side

Feature StratusLIVE 365 Salesforce Nonprofit Cloud Raiser’s Edge NXT Bloomerang
Best for Enterprise nonprofits Large, customizable solutions Major gift fundraising Small nonprofits
Integration Microsoft Dynamics 365 Salesforce ecosystem Blackbaud products Limited integrations
Donor Engagement Tools ✔ Advanced ✔ Customizable ✔ Specialized ✔ Basic
Fundraising Tools ✔ Comprehensive ✔ Customizable ✔ Strong ✔ Limited
Event & Volunteer Management ✔ Advanced ✔ Customizable ✔ Built-in ❌ Limited
AI & Engagement Scoring ✔ AI-powered ✔ AI-driven ❌ None ✔ Basic
Security & Compliance ✔ Microsoft Azure ✔ Salesforce Cloud ✔ Blackbaud Security ✔ Standard

 

So, how do you choose the right CRM for your nonprofit? It comes down to your organization’s size, complexity, and existing workflows. If you’re looking for a deeply integrated, AI-powered enterprise solution, StratusLIVE 365 is the best fit, especially if you already use Microsoft products. If you want something that’s highly customizable and you have the resources for a consultant to configure it, Salesforce Nonprofit Cloud is worth considering. Raiser’s Edge NXT is strong for major gift management, while Bloomerang is great for small teams focused on donor retention.

No matter which CRM you choose, investing in the right system can make all the difference in streamlining donor engagement, improving fundraising, and ultimately advancing your mission. If you want to see how StratusLIVE 365 could fit into your organization, now’s a great time to explore what it can do.

 

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